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Management of fibrosing alveolitis with polymyositis dermatomyositis
Author(s) -
Maccioni F. J.,
Colebatch H. J. H.
Publication year - 1990
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1990.tb00428.x
Subject(s) - medicine , polymyositis , prednisolone , dermatomyositis , cyclophosphamide , dermatology , myositis , chemotherapy
A 38‐year‐old man with polymyositis‐dermatomyositis developed acute life‐threatening fibrosing alveolitis. We report a two year follow‐up of this patient, during which control of alveolitis was obtained using prednisolone, and was maintained with the addition of cyclophosphamide. Relapse of myositis responded to increased prednisolone. Serial measurements of vital capacity and transfer factor assisted management of alveolitis, but changes in vital capacity preceded changes in transfer factor, and were more convenient to perform during frequent outpatient review.