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IMMUNE HEMOLYSIS AFTER AN ABO MISMATCHED RENAL TRANSPLANT
Author(s) -
PERKINS A. C.,
RICHARDS V. L.,
GIBSON J.,
JOSHUA D. E.,
JOHNSON J. R.,
KRONENBERG H.
Publication year - 1989
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1989.tb00275.x
Subject(s) - medicine , abo blood group system , hemolysis , immunology , immune system , abo incompatibility , renal transplant , kidney transplantation , kidney
We describe a case of immune hemolysis due to anti‐B occurring in a blood group B patient 16 days after a cadaveric renal transplantation from a blood group O donor. Transfusional support was initially required and the direct antiglobulin test (DAT) remained positive for 80 days. Cyclosporin A (CSA), which was used for rejection prophylaxis in this case, has unique immunosuppressive capabilities which protects transplanted organs from rejection, but which might permit this type of ‘graft versus host’ reaction.