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TREATMENT OF RESISTANT WALDENSTROM'S MACROGLOBULINEMIA WITH HIGH DOSE GLUCOCORTICOSTEROIDS
Author(s) -
JANE S. M.,
SALEM H. H.
Publication year - 1988
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1988.tb02249.x
Subject(s) - macroglobulinemia , medicine , waldenstrom macroglobulinemia , intensive care medicine , multiple myeloma , lymphoma
We examined the efficacy of high dose glucocorticosteroids in two patients with Waldenstrom's macroglobulinemia resistant to other forms of therapy. Both patients demonstrated marked falls in total protein, paraprotein and viscosity levels, after only short periods on this regimen. There was no significant toxicity. We conclude that high dose dexamethasone may offer significant benefits in the treatment of Waldenstrom's macroglobulinemia.