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LEAD INTOXICATION IN SYDNEY HARBOUR BRIDGE WORKERS *
Author(s) -
POLLOCK C. A.,
IBELS L. S.
Publication year - 1988
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1988.tb02239.x
Subject(s) - medicine , lead poisoning , chelation therapy , lead intoxication , lead (geology) , toxicity , lead exposure , chelation , surgery , toxicology , psychiatry , cats , chemistry , thalassemia , organic chemistry , geomorphology , geology , biology
Abstract: Thirty‐eight Sydney Harbour Bridge workers were assessed for possible lead intoxication. Forty‐seven per cent were found to have significant lead intoxication as assessed by calcium disodium edetate chelation (Ca EDTA) testing and were subsequently effectively and safely treated with Ca EDTA. The prevalence of neurological, constitutional, gastrointestinal and musculoskeletal symptoms was significantly greater in those with, than those without, lead toxicity. Although blood lead levels and, to a lesser extent, hematological parameters were of some use in diagnosis, they were not sufficiently sensitive and thus should not be used in screening workers at risk of lead intoxication. Ca EDTA testing remains the diagnostic method of choice. Patients exposed to lead dust and fumes, in whom symptoms of lead intoxication are present, should undergo such testing and if a positive result is obtained, then EDTA chelation therapy should be instituted. (Aust NZ J Med 1988; 18: 46–52).