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PAPILLARY NECROSIS ASSOCIATED WITH RIFAMPICIN THERAPY
Author(s) -
LAI F. MACMOUNE,
LAI K. N.,
CHONG Y. W.
Publication year - 1987
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1987.tb05055.x
Subject(s) - medicine , discontinuation , rifampicin , tuberculosis , acute tubular necrosis , interstitial nephritis , pathological , renal function , necrosis , kidney , focal segmental glomerulosclerosis , pathology , glomerulonephritis , surgery
We report a patient who developed progressive renal failure following 13 months of rifampicin therapy for renal tuberculosis. The renal function continued to deteriorate despite the discontinuation of rifampicin. Renal pathology did not demonstrate any evidence of tuberculosis of the kidney but revealed the unique pathological finding of glomeruloscterosis, granulomatous interstitial nephritis, and extensive papillary necrosis.