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CHRONIC EOSINOPHILIC PNEUMONIA IN A PATIENT WITH ATAXIA TELANGIECTASIA
Author(s) -
ZAGAMI A. S.,
COLEBATCH H. J. H.,
WAKEFIELD D.
Publication year - 1987
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1987.tb01266.x
Subject(s) - ataxia telangiectasia , medicine , pneumonia , ataxia , eosinophilic , telangiectasia , eosinophilic pneumonia , immunology , pulmonary eosinophilia , dermatology , pathology , respiratory disease , eosinophil , asthma , lung , dna , genetics , dna damage , psychiatry , biology
The first reported case of chronic eosinophilic pneumonia in a patient with ataxia telangiectasia is described. The patient displayed the immunoglobulin deficiencies and abnormalities of lymphocyte numbers characteristic of ataxia telangiectasia. Treatment with corticosteroids led to a dramatic recovery. The proposed pathogenetic mechanisms of chronic eosinophilic pneumonia are discussed in the light of the immunological abnormalities associated with ataxia telangiectasia.