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SERUM FRUCTOSAMINE AS A SCREENING METHOD FOR DIABETES MELLITUS IN PATIENTS WITH SUSPECTED ACUTE MYOCARDIAL INFARCTION
Author(s) -
KYLE C.,
BAKER J.,
METCALF P.,
JOHNSON R.,
NORRIS R.
Publication year - 1987
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1987.tb00098.x
Subject(s) - fructosamine , medicine , diabetes mellitus , myocardial infarction , population , cardiology , heart failure , endocrinology , environmental health
It is important to identify diabetic patients in a coronary care population because they have a higher risk of suffering congestive heart failure, dysrhythmias and death following myocardial infarction. In order to determine the most efficient screening method for diabetes, we compared fructosamine and glucose measurements on admission blood specimens from 256 consecutive patients. Of 15 (5.9%) known diabetic patients, 12 had glucose results >7.8 mmol/l and nine had fructosamine levels >2.87 mmol/l. However, elevated glucose results were also found in a high proportion (49.2%) of patients with no previous history of diabetes. We performed glucose tolerance tests in 107 patients after discharge to determine the frequency of false‐positive observations. Fructosamine yielded five (4.6%) false‐positive results, whereas plasma glucose yielded 47 (43.9%) false‐positive observations. We conclude that serum fructosamine provides a more specific screening method for diabetes in this population because the results are unaffected by stress hyperglycemia. (Aust NZ J Med 1987; 17: 467–471.)