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NIFEDIPINE HEPATITIS
Author(s) -
SHAW D. R.,
MISAN G. M. H.,
JOHNSON R. D.
Publication year - 1987
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1987.tb00088.x
Subject(s) - medicine , nifedipine , chills , eosinophilia , nausea , anorexia , adverse effect , liver function , hepatitis , liver function tests , liver biopsy , anesthesia , gastroenterology , biopsy , calcium
An 80‐year‐old woman developed acute hepatitis following her first exposure to nifedipine. This adverse effect was characterised by fever, chills, anorexia, nausea, liver tenderness, hepatitic liver function tests and peripheral blood eosinophilia. On liver biopsy the portal tracts were expanded with a mixed inflammatory cell infiltrate rich in eosinophils. The potential for the occurrence of this adverse effect must increase with the current expansion of indications for the use of nifedipine.