Premium
ANTIBODY PATTERNS IN THE SEROLOGICAL DIAGNOSIS OF ACUTE LYMPHADENOPATHIC TOXOPLASMOSIS
Author(s) -
JOHNSON A. M.,
GU Q. M.,
ROBERTS H.
Publication year - 1987
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1987.tb00082.x
Subject(s) - serology , medicine , toxoplasmosis , antibody , immunology , specific antibody
Sera from six patients at various stages of acute lymphadenopathic toxoplasmosis were tested using nine different types of test currently available for the serological diagnosis of the disease. A diagnosis was made on positive serology in three of the patients. The antibody patterns of two of these patients were studied over a period of six months and the third was studied over two months. A diagnosis was made on lymph node morphology in the other three cases. Two serum samples were tested from each of these patients. The results obtained suggest that a rationalisation of the types of test used should be encouraged and that an enzyme‐linked immunosorbent assay (ELISA) for parasite‐specific IgG and an antibody class capture ELISA for parasite‐specific IgM are sufficient to confirm the diagnosis of acute lymphadenopathic toxoplasmosis.