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ADULT HENOCH‐SCHÖNLEIN NEPHRITIS
Author(s) -
FAULL R. J.,
AARONS I.,
WOODROFFE A. J.,
CLARKSON A. R.
Publication year - 1987
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1987.tb00072.x
Subject(s) - medicine , nephritis , abnormality , presentation (obstetrics) , disease , retrospective cohort study , biopsy , renal biopsy , stage (stratigraphy) , pathology , surgery , paleontology , psychiatry , biology
A retrospective study was performed of all patients at the Royal Adelaide Hospital over a ten‐year period with biopsy proven Henoch‐Schonlein nephritis. The records of 27 patients were examined, with emphasis on clinical and histopathological presentation, treatment and outcome. A scheme for assessing glomerular histology is presented, and severity correlated with prognosis of the disease. At presentation unfavourable prognostic indicators were acute renal impairment, crescents in greater than 20% of glomeruli, and severe glomerular histological lesions. Four patients died as a result of the disease, and 20 of the patients had evidence of continued renal abnormality at follow‐up. Adult Henoch‐Schénlein nephritis is a potentially catastrophic disease, and requires careful assessment at presentation.