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AMINOPHYLLINE IN ACUTE ASTHMA
Author(s) -
OLSON L. G.
Publication year - 1987
Publication title -
australian and new zealand journal of medicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1987.tb00063.x
Subject(s) - aminophylline , medicine , citation , library science , computer science
It is widely believed that theophylline is a valuable addition to beta-agonists in the treatment of asthma. This is true when beta-agonists are given in low doses, but available evidence suggests that theophylline adds little or nothing to the effect of maximal doses of beta-agonists. Clinical trials, albeit some with limitations, in acute asthma support the view that theophylline confers no benefit on patients treated with high-dose beta-agonists. As theophylline is a difficult drug to use safely, and its toxicity is serious, its use should be confined to unusual circumstances, and the dose should be small.