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CYTOPHAGIC PANNlCULITIS
Author(s) -
MARCH L. M.,
WEBB J.,
ECKSTEIN R. P.
Publication year - 1986
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1986.tb01197.x
Subject(s) - medicine , panniculitis , erythema nodosum , histiocyte , pathology , atypical lymphocyte , differential diagnosis , dermatology , bone marrow , lymphoma , disease
A 60 year old woman developed generalised erythema nodosum‐like lesions together with hectic fever, lymphadenopathy, and hepatitis. Biopsies revealed lobular panniculitis with a benign histiocytic infiltrate and prominent phagocytosis in subcutaneous sites, lymph nodes, and bone marrow. All immunological, serological, and culture studies were negative, apart from throat isolation of herpes simplex. The patient responded to high‐dose corticosteroids. The case illustrates the differential diagnosis of lobular panniculitis, with histiocytic infiltrate and cytophagocytosis. These combined features are consistent with the recently described syndromes of cytophagic panniculitis and virus‐associated hemophagocytic syndrome.