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RESPONSE OF REFRACTORY ANEMIA TO LOW‐DOSE CYTOSINE ARABINOSIDE
Author(s) -
GALLO J. H.,
ROZENBERG M. C.
Publication year - 1986
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1986.tb01158.x
Subject(s) - medicine , refractory (planetary science) , cytosine , anemia , refractory anemia , myelodysplastic syndromes , blood transfusion , gastroenterology , bone marrow , dna , genetics , physics , astrobiology , biology
Two elderly patients with transfusion‐dependent refractory anemia due to myelodysplastic syndromes were treated with a course of low‐dose subcutaneous cytosine arabinoside in an attempt to reduce their transfusion requirements. Following treatment, they required no transfusions for over six months. The treatment was well tolerated, but was associated with initial myelosuppression.