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DIFLUNISAL‐INDUCED NEUTROPENIA
Author(s) -
McLEAN C. A.,
BEGLEY C. G.,
HARRIS R. A.
Publication year - 1986
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1986.tb00046.x
Subject(s) - medicine , neutropenia , granulopoiesis , diflunisal , bone marrow , drug , immunology , pharmacology , surgery , chemotherapy , haematopoiesis , biology , genetics , stem cell
We report a case of neutropenia associated with the use of diflunisal. The neutropenia occurred with initial administration and on subsequent inadvertent rechallenge with the drug. Bone marrow biopsy showed active granulopoiesis and an immune‐mediated mechanism for this response is postulated.