Premium
ACUTE ENCEPHALOPATHY AND DEATH DUE TO PETROL SNIFFING: NEUROPATHOLOGICAL FINDINGS
Author(s) -
KAELAN C.,
HARPER C.,
VIEIRA B. I.
Publication year - 1986
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1986.tb00043.x
Subject(s) - chromatolysis , medicine , sniffing , toxic encephalopathy , encephalopathy , carbon monoxide poisoning , cerebellum , cerebral cortex , poison control , pathology , neuroscience , psychiatry , anatomy , medical emergency , spinal cord , biology
A 25 year old man with a five year history of petrol sniffing developed an acute encephalopathy with abnormal body movements and died of aspiration pneumonia. Neuropathological findings included chromatolysis of neurons in the reticular formation and cerebral cortex and loss of neurons in the h3‐5 sector of Ammon's horn and the cerebellum. Toxicological studies suggest that the encephalopathy is caused by the tetraethyl‐lead additive in the petrol. These data support previous human and experimental studies.