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GOLD‐INDUCED BONE MARROW APLASIA: SUCCESSFUL TREATMENT WITH ANTITHYMOCYTE GLOBULIN
Author(s) -
McGIRR E. E.,
MANOHARAN A.,
WEGMAN E.,
EDMONDS J. P.
Publication year - 1985
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1985.tb04018.x
Subject(s) - medicine , pancytopenia , bone marrow aplasia , aplasia , rheumatoid arthritis , bone marrow , bone marrow transplantation , surgery , aplastic anemia
A patient receiving gold treatment for rheumatoid arthritis developed sudden severe pancytopenia secondary to bone marrow aplasia. She required extensive hematological support but was unsuitable for bone marrow transplantation. Although early use of large doses of a chelating agent did not change the hematological parameters, subsequent use of antithymocyte globulin has been associated with substantial hematological improvement.