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CHARCOAL HEMOPERFUSION TREATMENT OF SEVERE THEOPHYLLINE TOXICITY
Author(s) -
KELLY W. J. W.,
PARKIN W. G.
Publication year - 1985
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1985.tb02743.x
Subject(s) - hemoperfusion , theophylline , medicine , hypokalemia , charcoal , toxicity , anesthesia , activated charcoal , intensive care medicine , surgery , hemodialysis , chemistry , organic chemistry , adsorption , materials science , metallurgy
:A 38 year old man was admitted eight hours after taking ten grams of theophylline. The plasma concentration of theophylline on admission was 732 fjmol/l. In view of the patient's continuing clinical deterioration, charcoal hemoperfusion was undertaken. This led to a rapid fall in plasma theophylline concentrations and improvement in clinical signs. It is suggested that characoal hemoperfusion has a role in the severely theophylline toxic patient in whom standard conservative measures are failing. The patient's hyperglycemia, metabolic acidosis, and hypokalemia are discussed.