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RAPIDLY PROGRESSIVE FATAL PULMONARY INFILTRATION BY LYMPHOMA
Author(s) -
KENNEDY P.,
JOSHUA D. E.,
BUCK M.,
KRONENBERG H.
Publication year - 1985
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1985.tb02738.x
Subject(s) - medicine , lymphoma , pathology , infiltration (hvac) , sputum , lung , differential diagnosis , biopsy , lung biopsy , chemotherapy , tuberculosis , physics , thermodynamics
:Two patients with diffuse lymphoma, one diffuse large cell and the other diffuse mixed, large and small cell, developed an illness characterised by a high swingeing fever and a pulmonary infiltrate. In both patients there was clinical evidence of chemotherapy‐induced tumour response elsewhere at the time lung infiltrates progressed. Blood and sputum cultures, bronchial washings, and, in one case, trans‐bronchial lung biopsy did not establish a diagnosis and there was progressive clinical deterioration. Post mortem examination showed widespread involvement of both lungs with lymphoma. The differential diagnosis of fever and pulmonary infiltrates in patients with diffuse lymphoma is discussed, in particular the possibility of this being due to rapidly progressive lymphom