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NEUROLOGICAL TOXICITY ASSOCIATED WITH VIDARABINE (ADENINE ARABINOSIDE) THERAPY
Author(s) -
COLLIG P. J.,
SORRELL T. C.
Publication year - 1983
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1983.tb02618.x
Subject(s) - vidarabine , medicine , toxicity , allopurinol , myoclonic jerk , dermatology , pediatrics , surgery , chemotherapy , anesthesia , myoclonus , fludarabine , cyclophosphamide
Disorientation, myoclonic jerks, generalised rigidity and tremor developed in a young woman while on treatment with vidarabine for disseminated cutaneous varicella. Residua were still present 11 months later. She had normal renal function and was being treated with relatively low dose vidarabine therapy. A possible drug interaction with allopurinol is described.