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Primary Hyperaldosteronism in Pregnancy
Author(s) -
Hammond T. G.,
Buchanan J. D.,
Scoggins B. A.,
Thatcher R.,
Whitworth J. A.
Publication year - 1982
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1982.tb03842.x
Subject(s) - medicine , hyperaldosteronism , pregnancy , gestation , post partum , plasma renin activity , aldosterone , primary aldosteronism , postpartum period , gynecology , endocrinology , surgery , renin–angiotensin system , blood pressure , genetics , biology
Primary hyperaldosteronism in pregnancy. T. G. Hammond, J. D. Buchanan, B. A. Scoggins, R. Thatcher and J. A. Whitworth, Aust. N.Z. J. Med., 1982, 12 , pp. 537–539. We report a case of primary hyperaldosteronism in a 37‐year‐old woman presenting early in pregnancy with hypertension and hypokalaemia. Plasma renin concentration was suppressed and unaffected by sodium restriction or upright posture at 16 and 35 weeks gestation, or seven days post‐partum. Recumbent plasma aldosterone was elevated, and normal postural response lost both at 35 weeks gestation and seven days post‐partum. Vaginal delivery, following induction at 38 weeks, was uncomplicated. Two months postpartum C.T. scan and adrenal venous catheterisation studies indicated a left sided adenoma and left adrenalectomy was performed. Within seven days the patient was normotensive with normal serum potassium and urinary aldosterone on no treatment.