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Exclusion of Leukaemic Meningitis by Quantitation of T and B Lymphocytes in Cerebrospinal Fluid
Author(s) -
Harrison P. B.,
Cripps A. W.
Publication year - 1982
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1982.tb02479.x
Subject(s) - medicine , cerebrospinal fluid , lymphoma , immunology , lymphocyte , meningitis , pathology , central nervous system , lymphatic system , peripheral blood , pediatrics
Exclusion of leukaemic meningitis by quantitation of T and B lymphocytes in cerebrospinal fluid. P. B. Harrison and A. W. Cripps, Aust. N.Z. J. Med., 1982, 12, pp. 286–287. Involvement of the central nervous system (CNS) in chronic lymphatic leukaemia (CLL) is rare. 1 However, when a patient with CLL presented with meningeal symptoms and a high CSF lymphocyte count in the absence of identifiable infection, meningeal leukaemia was considered the most likely diagnosis. Subsequent quantitation of T and B lymphocytes in the blood and CSF was found to be a most valuable aid in excluding the diagnosis, and later a cryptococcal infection was proven. This case is reported to draw attention to the value of T and B lymphocyte quantitation where difficulty is experienced in interpretation of cells in CSF in patients with leukaemia or lymphoma.