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Radiation Veno‐Occlusive Liver Disease
Author(s) -
Rowland R.,
Pieterse A. S.,
Kimber R. J.,
Ward G.
Publication year - 1981
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1981.tb04626.x
Subject(s) - medicine , jaundice , ascites , radiation therapy , hepatic veno occlusive disease , lymphoma , disease , liver disease , surgery , radiology , gastroenterology , hematopoietic stem cell transplantation
Two fatal cases of veno‐occlusive disease (VOD) of the liver following whole‐abdominal irradiation for malignant lymphoma are described. This occurred despite a radiotherapy programme designed to reduce the toxic effect of irradiation to the liver. The clinical picture of rapid weight gain, progressive ascites, jaundice, raised alkaline phos‐phatase and thrombocytopenia following abdominal radiotherapy should alert the clinician to the possibility of irradiation induced VOD .