Premium
Cell‐Mediated Immunity in Glomerulonephritis
Author(s) -
Thomson N. M.,
Kraft N.,
Atkins R. C.
Publication year - 1981
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1981.tb03572.x
Subject(s) - glomerulonephritis , medicine , humoral immunity , immunology , pathogenesis , immunity , cell mediated immunity , disease , lesion , immune system , pathology , kidney
In about 30% of cases of glomerulonephritis. there is little or no evidence that humoral immunity has a role in the pathogenesis of the disease. There is now mounting evidence that cell‐mediated immunity (CMI) plays a role in this group of glomerulonephritides, particularly in minimal lesion glomerulonephritis. Moreover, there is some evidence that CMl may also augment injury in glomerulonephritis, primarily induced by a humoral mechanism .