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Aspects of Renal Bone Disease
Author(s) -
Cochran M.
Publication year - 1981
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1981.tb03558.x
Subject(s) - medicine , osteomalacia , osteosclerosis , renal osteodystrophy , secondary hyperparathyroidism , renal tubular acidosis , hyperparathyroidism , bone disease , cortical bone , population , calcium , disease , kidney disease , endocrinology , pathology , osteoporosis , parathyroid hormone , acidosis , environmental health
In advanced chronic renal failure hypo‐calcaemia can be due to a combination of factors. These include decreased delivery of calcium into the plasma and increased renal tubular leakage of calcium. The secondary hyperparathyroidism that follows the hypo‐calcaemia leads to osteosclerosis, probably by movement of cortical mineral into trabecular bone. In the dialysis population, an atypical and readily identifiable form of osteomalacia sometimes occurs and is probably secondary to a water‐borne toxin .