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Failure of Oral Versus Parenteral Corticosteroids in a Case of Acute Inflammatory Polyradiculoneuropathy (GuiIlain‐Barré Syndrome)
Author(s) -
Brumback R. A.
Publication year - 1980
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1980.tb03718.x
Subject(s) - medicine , prednisone , prednisolone , polyradiculoneuropathy , corticosteroid , anesthesia , respiratory failure , surgery , guillain barre syndrome , pediatrics
Summary: Failure of oral versus parenteral corticosteroids in a case of acute inflammatory polyradiculoneuropathy (Guillain‐Barré syndrome). R. A. Brumback, Aust. N.Z. J. Med ., 1980. 10, pp. 224–226. A case of acute inflammatory polyradiculoneuropathy (IPN, Guillain‐Barré syndrome) not responding to oral corticosteroids but showing marked improvement on parenteral corticosteroids is reported. Oral prednisone 60 mg/day was begun on hospital admission and increased after one week to 100 mg/day; however, the patient's respiratory function, demonstrated by forced vital capacity, continued to deteriorate. lmprovement was noted when the patient was switched to intravenous methyl‐prednisolone 100 mglday. Further attempts to use oral corticosteroids (including oral methyl‐prednisolone 96 mg/day) resulted in deterioration of the patient's function