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False Positive and Negative Hemoccult Reactions on a Normal Diet and Effect of Diet Restriction
Author(s) -
Bassett M. L.,
Goulston K. J.
Publication year - 1980
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1980.tb03408.x
Subject(s) - medicine , occult , gastroenterology , pathology , alternative medicine
Summary: False positive and negative hemoccult reactions on a normal diet and effect of diet restriction. M. L. Bassett and K. J. Goulston, Aust. N.Z. J. Med . 1980, 10 . pp. 1–4. The reliability of Hemoccult, a guaiacimpregnated slide for detecting faecal occult blood, was assessed on both normal and restricted diets. Two‐hundred‐and‐twenty‐five faecal samples were obtained from 40 patients on a normal diet, and 115 samples from 20 patients on a restricted diet. A single Hemoccult I test was performed on each sample. Faecal blood was quantitated by 51 Cr red cell labelling. On a normal diet, the false positive rate was 11%. This reduced to 2% on a high fibre diet free of red meat and raw fruit and vegetables. This false positive rate is lower than has been previously reported for other : more widely‐used, occult blood tests. The overall false negative rate was 48%; this diminished with increasing faecal blood loss.