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Early Diagnosis of Addison's Disease; Pigmentation as sole symptom
Author(s) -
Strakosch C. R.,
Gordon R. D.
Publication year - 1978
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1978.tb04510.x
Subject(s) - addison's disease , medicine , anorexia , weakness , disease , aldosterone , adrenocortical insufficiency , girl , endocrinology , urinary system , pediatrics , adrenal insufficiency , surgery , psychology , developmental psychology
Summary: Early diagnosis of Addison's disease; pigmentation as sole symptom. A diagnosis of primary adrenocortical insufficiency was made in a shapely, suntanned girl whose sole complaint was increasing pigmentation. Plasma Cortisol was low in spite of markedly elevated levels of ACTH. Plasma Cortisol, urinary 17‐oxogenic steroids and urinary aldosterone did not respond to three days of ACTH stimulation. Addison's disease can be diagnosed and treated before development of anorexia, weight loss, weakness and other classical symptoms.