Premium
Sideroblastic Anaemia and Leukaemia in Multiple Myeloma
Author(s) -
Phadke K. P.,
Kwan Y. L.,
Young S. G.
Publication year - 1978
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1978.tb02596.x
Subject(s) - medicine , multiple myeloma
Summary: Sideroblastic anaemia and leukaemia in multiple myeloma. K. P. Phadke, Y. L. Kwan and S. G. Young, Aust. N.Z. J. Med., 1978, 8, pp. 539–543. Two patients with IgA myeloma and one patient with kappa light chain disease developed sideroblastic anaemia from two to four years after the initial diagnosis. All had previously received radiotherapy and chemotherapy (melphalan and prednisone). In two patients the myeloma was quiescent when the sideroblastic change occurred. Leukaemia occurred in two patients two and seven months respectively after the diagnosis of sideroblastic anaemia was made. In one of them, the myeloma became active again at the same time. The development of sideroblastic anaemia may be a preleukaemic event and may be recognised by the appearance of a dimorphic blood film.