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Primary Amyloidosis with Cardiac Involvement Diagnosed by Left Ventricular Endomyocardial Biopsy
Author(s) -
Chan William,
Ikram Hamid
Publication year - 1977
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1977.tb04411.x
Subject(s) - medicine , endomyocardial biopsy , cardiac amyloidosis , pathognomonic , amyloidosis , biopsy , prednisone , restrictive cardiomyopathy , cardiomyopathy , al amyloidosis , heart failure , cardiology , disease , antibody , immunology , immunoglobulin light chain
Summary:Primary amyloidosis with cardiac involvement diagnosed by left ventricular endomyocardial biopsy. W. Chan and H. Ikram, Aust. N.Z. J. Med. , 1977, 7 , pp. 427–430. A case of primary amyloidosis is described. The patient presented with the nephrotic syndrome and later developed heart failure. Left ventricular endomyocardial biopsy was performed and haemodynamic data were recorded. The findings were those of a ‘restrictive’ cardiomyopathy. Histology of the biopsy was pathognomonic of amyloid involvement of the heart. The patient was started on chemotherapy consisting of prednisone, penicillamine, me/pha/an and fluoxymesterone. This case demonstrates the ability of endomyocardial biopsy in arriving at a definitive diagnosis in this patient.