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The Probable Significance of Hypertriglyceridaemia in Viral Hepatitis*
Author(s) -
Aiyathurai J. E. J.,
Sentheshanmuganathan S.
Publication year - 1976
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1976.tb03986.x
Subject(s) - transamination , alanine , alanine transaminase , medicine , viral hepatitis , biochemistry , alanine aminotransferase , transaminase , substrate (aquarium) , endocrinology , biology , amino acid , enzyme , ecology
Summary: The probable significance of hypertriglyceridaemia in viral hepatitis. J. E. J. Aiyathurai and S. Sentheshanmuganathan, Aust. N.Z. J. Med., 1976, 6, pp. 529–532. It is proposed that the raised serum glutamic pyruvic transaminase activity (SGPT) in viral hepatitis reflects an adaptive increase in glutamic pyruvic transaminase in muscle for the increased transamination of alanine for post‐absorptive glucose homeostasis. However, in a disease where the SGPT is elevated for four to six weeks, muscle cannot be an indefinite source of alanine unless it could, concurrently, resynthesize alanine.