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Hepatitis B Antigen Subtypes in Asymptomatic Carriers in the Solomon Islands1,*
Author(s) -
Williams H.,
Mazzur S.
Publication year - 1976
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1976.tb03656.x
Subject(s) - antigen , virology , medicine , asymptomatic carrier , asymptomatic , hepatitis b , hepatitis b virus , titer , hepatitis , virus , immunology
Summary: Hepatitis B antigen subtypes in asymptomatic carriers in the Solomon Islands. H. Williams and S. Mazzur Three hundred and fifty‐three students attending King George VI School in Honiara, British Solomon Islands Protectorate, were tested by immunodiffusion for hepatitis B surface antigen (HB, Ag). The prevalence of HB Ag was 13% and the antigen was found more frequently in males. Twenty‐seven samples which contained high titers of antigen were subtyped to define those subtype combinations present in the BS/P. The most frequent antigen was adr+yw‐. This combination is a/so common in Thai/and and Japan. The second most prevalent comb/nation was ayw+dr‐. The antigenic determinants also occurred less frequently as adw+yr‐, adwr+y‐, and awr+dy‐. These unusual samples which contain both w and r may be the result of mixed particles, recombination of virus, mixing of viral proteins in doubly infected cells or extracellular aggregation of mixed viral products.