Premium
Cold Agglutinin Formation in Patients Undergoing Haemodialysis. A Possible Relationship to Dialyser Re‐use
Author(s) -
Harrison Pamela Brawdley,
Jansson Kay,
Kronenberg Harry,
Mahony John Francis,
Tillert David
Publication year - 1975
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1975.tb04567.x
Subject(s) - medicine , cold agglutinin , dialysis , extracorporeal , antibody , surgery , intensive care medicine , immunology
Summary: Cold agglutinin formation in patients undergoing haemodialysis. A possible relationship to dialyser re‐use. Cold agglutinins with anti‐N characteristics were shown to develop in as short a time as four months in patients on home dialysis. It appeared that the development of such antibodies is related to dialyser re‐use. Those who were treated without re‐using their dialyser did not develop these antibodies. Anti‐N may cause early graft failure associated with agglutination in a cold allograft. Moreover, if these antibodies develop in patients on dialysis there may be problems with extracorporeal dialysis and blood transfusion.