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Elevation of Serum Bilirubin and Blood Urea in Pneumonia
Author(s) -
Douglas R. M.,
Devitt L.,
Macartney B.
Publication year - 1974
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1974.tb03202.x
Subject(s) - medicine , bilirubin , pneumonia , gastroenterology , urea , bacteremia , blood urea nitrogen , pneumococcal pneumonia , streptococcus pneumoniae , kidney , antibiotics , biochemistry , chemistry
Summary: In a study of adult patients with pneumonia in Papua New Guinea, the serum bilirubin was elevated in 45% of 42 bacteremic and 23% of 402 nonbacteremic cases and blood urea was elevated in 55% of bacteremic and 26% of non‐bacteremic episodes. Both abnormalities occurred more frequently in patients with extensive consolidation and neither was related exclusively to pneumococcal infection. Review of available evidence suggests that both prerenal and renal factors are operative in causing elevation of blood urea in pneumonia and that, similarly, elevation of bilirubin is of complex origin resulting from both pre‐hepatic and hepatic dysfunction.