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Regional Hepatic Blood Flow Studied by Intrahepatic Injection of 133 Xenon in Normals and in Patients with Primary Carcinoma of the Liver, with Particular Reference to the Effect of Hepatic Artery Ligation
Author(s) -
Plengvanit Ukrist,
Suwanik Romsai,
Chearanai Orapan,
Intrasupt Somlak,
Sutayavanich Sahas,
Kalayasiri Chiamchit,
Viranuvatti Vikit
Publication year - 1972
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1972.tb03907.x
Subject(s) - medicine , ligation , blood flow , artery , cirrhosis , carcinoma , collateral circulation , parenchyma , liver parenchyma , angiography , pathology , radiology
Summary: Measurement of regional hepatic blood flow using radioactive xenon by Gelin's method was studied in 20 controls and 21 patients with primary carcinoma of the liver, eight of whom had associated cirrhosis. The mean value of blood flow for controls was 28.77±9.50 ml/min/100 g, for carcinomatous nodules 12.21±5.83, for normal areas in the liver with primary carcinoma 37.88±12.88 and for cirrhotic areas in the liver with primary carcinoma 21.50±10.16. The blood flow of carcinomatous tissue is significantly less than of normal parenchyma and this can be explained by the histopathological and angiographic findings. Temporary reduction in the blood flow was obtained by ligation of the hepatic artery and postoperative angiography demonstrated the formation of collateral arteries to the liver.