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AN AGGRESSIVE STROMAL SARCOMA OF THE BREAST: A CASE REPORT AND ROLE OF RADIOTHERAPY
Author(s) -
Imisairi A. H.
Publication year - 2009
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/j.1445-2197.2009.04913_13.x
Subject(s) - medicine , axillary lymph nodes , radiation therapy , sarcoma , wide local excision , biopsy , mastectomy , axillary lymphadenopathy , stromal cell , radical mastectomy , radiology , metastasis , breast cancer , surgery , pathology , cancer
Primary breast sarcoma is very rare and aggressive that comprises 0.5–1% of all breast neoplasms. Most of the series include both stromal and cystosarcoma phylloides and only few reports based on primary stromal sarcoma of the breast solely. The mode of treatment is still uncertain and the role of radiotherapy remains questionable. Case Report: We report a case of a stromal sarcoma of the breast in a 62 year‐old woman who was referred to our centre because of rapidly enlarging mass of the right breast for 6 months. The mass was 16 × 15 × 15 cm in size, fungating with overlying skin ulceration. A tru cut biopsy revealed malignant lesion most probably stromal sarcoma or malignant phylloides. Mastectomy of the right breast with axillary clearance with split skin graft was performed and pathologic examination demonstrated primary stromal sarcoma of the right breast with involvement of the pectoralis major. No axillary lymph nodes involvement was noted. The patient was subsequently undergone 20 courses of radiotherapy to the right chest wall. CT scan of the thorax and abdomen 6 months after that were normal and it was repeated yearly for 3 consecutive years which revealed no evidence of distant metastasis. Conclusion: The aggressiveness of breast stromal sarcoma mandates adequate surgical resection to achieve local control. Despite radiotherapy shows good respond in this case, its role is still debatable and more series need to be reviewed to justify the indication.