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TOTAL MESORECTAL EXCISION: EVALUATING THE EVIDENCE
Author(s) -
McCall John L.
Publication year - 1997
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1997.tb04605.x
Subject(s) - mesorectum , medicine , total mesorectal excision , colorectal cancer , pathological , rectum , clinical trial , surgery , randomized controlled trial , cancer
The present paper reviews information from pathological and clinical studies examining the role of total mesorectal excision (TME) in the treatment of rectal cancer. The pathological studies provide information about the spread of rectal cancer within the mesorectum, and the adequacy of excision obtained with conventional surgery and TME. The clinical studies provide information about the safety of TME and the reported local recurrence rates. Taken together, these studies provide a rationale for using TME to resect rectal cancers in the distal two‐thirds of the rectum, despite the absence of direct evidence from randomized controlled trials.