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INDICATIONS FOR LAPAROSCOPIC PELVIC LYMPH NODE DISSECTION IN THE STAGING OF PROSTATE CANCER
Author(s) -
Patel Manish I.,
Katelaris Philip M.
Publication year - 1995
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1995.tb00618.x
Subject(s) - medicine , dissection (medical) , lymph node , prostatectomy , lymphadenectomy , stage (stratigraphy) , prostate cancer , prostate , surgery , radiology , frozen section procedure , prostate specific antigen , cancer , paleontology , biology
Laparoscopic pelvic lymph node dissection is increasing in popularity, in the absence of validated surgical indications. This retrospective study was performed to identify those patients who would benefit from laparoscopic pelvic lyrnphadenectomy. The case notes of 50 patients who underwent bilateral open pelvic lymphadenectorny with frozen section examination were reviewed. The patients were staged clinically as having A2 (16), B1 (20) and B2 (14) prostate cancer. Except for the two patients who had macroscopically involved pelvic lymph nodes at operation, all proceeded to total prostatectorny. Six patients were found to have positive pelvic nodes. Of the six, four patients were clinical stage B2, one was B1 and one was A2. The Gleason score of two of these six patients was greater than seven. The prostate specific antigen (PSA) levels correlated more with high turnour volume (i. e. grade C) rather than with D1 disease. Frozen section at the time of lyrnphadenectomy had a false negative rate of 2 of 6. We conclude that laparoscopic pelvic lymph node dissections (LPLND) should be performed where there is a high likelihood of nodal disease, viz. bulky tunours, poorly differentiated histology and a high PSA reading. We consider that such selective use of LPLND optimizes its diagnostic utility while minimizing its unnecessary application.