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EXTRADURAL MALIGNANT LYMPHOMA ASSOCIATED WITH SPINAL CORD COMPRESSION
Author(s) -
Crowley K. S.,
Miliauskas J.,
North J. B.,
Esterman A.,
Leong A. SY.
Publication year - 1992
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1992.tb06938.x
Subject(s) - medicine , lymphoma , malignancy , spinal cord compression , laminectomy , malignant lymphoma , surgery , non hodgkin's lymphoma , spinal cord , psychiatry
Cord compression was noted in 26 patients with extradural malignant lymphoma. There were 19 cases of non‐Hodgkin's lymphoma and seven cases of Hodgkin's disease. Eighteen cases of non‐Hodgkin's lymphoma had intermediate or high grade malignancy types according to the Working Formulation Lymphoma Classification. These patients represented 28% of all extradural malignant tumours seen at the Royal Adelaide Hospital (RAH) and 2.5% of all patients with malignant lymphoma, during an 11 year period. The patients were classified in three presenting groups: Group A, six patients with primary extranodal extradural lymphoma; Group B, nine patients with bolh extradural lymphoma and disseminated disease at initial presentation; and Group C, 11 patients who developed extradural lymphoma during the course of established disease. Only classification by groups appeared to affect survival time. Group A had the most favourable prognosis, with a 5 year survival of 83%. Five of the Group A patients had a relapse of lymphoma; four at distant sites and one in the retroperitoneum. Laminectomy was essential to provide a diagnosis in Group A patients. The most useful warning symptom of impending spinal cord compression was back and/or radicular pain, which preceded neurological deficit either by days or by up to 5 years. Plain spinal X‐rays were abnormal in 64% of cases, emphasizing the value of this simple procedure.