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EFFECT OF HEPATIC CRYOTHERAPY ON SERUM CEA CONCENTRATION IN PATIENTS WITH MULTIPLE INOPERABLE HEPATIC METASTASES FROM COLORECTAL CANCER
Author(s) -
Charnley R. M.,
Thomas M.,
Morris D. L.
Publication year - 1991
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1991.tb00127.x
Subject(s) - medicine , cryotherapy , carcinoembryonic antigen , colorectal cancer , cryosurgery , cancer , surgery
Eleven patients with multiple hepatic metastases from colorectal cancer, all judged inoperable, were treated by cryotherapy using a probe through which liquid nitrogen was circulated using a single freeze thaw sequence. Localization of metastases, positioning of the probe and monitoring of ice ball size was by intra‐operative ultrasound. Serum carcinoembryonic antigen (CEA) was measured in these patients: there was a postoperative fall in all but two. In all but one, there has been a subsequent rise. Speed and degree of rise of CEA varied between patients. Serial CEA may be an effective means of monitoring the effect of hepatic cryotherapy.