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PERIOPERATIVE BLOOD TRANSFUSION AND GASTRIC CANCER: ADVERSE EFFECTS OR UNFAVOURABLE CONDITIONS OF PRETREATMENT?
Author(s) -
Yamaguchi Koji,
Tokui Noritaka,
Maeda Shogo,
Kominami Tatsuya,
Nakamura Kazuhiko,
Kitamura Katsutoshi
Publication year - 1990
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1990.tb07471.x
Subject(s) - medicine , perioperative , blood transfusion , adverse effect , confounding , cancer , surgery , anesthesia
The use of perioperative blood transfusion (PBT), the immunological status pre‐operatively and at discharge from hospital. and the clinical course were examined retrospectively in 124 patients who underwent ‘curative’resection for gastric cancer at Shinkokura Hospital, Japan from 1979 to 1988. The general condition of patients with PBT was worse than that of those without PBT and the pre‐operative immunological status of patients with PBT was less favourable than that of those without PBT. At the time of discharge from hospital the immunological condition remained worse for patients who had been given PBT. Thc clinical course of patients with PBT was significantly worse. A dose‐response relationship was evident but the types of blood products did not influence the outcome. Cox regression analysis adjusting for potentially confounding prognostic factors revealed that the clinical course was not altered by perioperativc blood transfusion itself. These observations do not support the idea of adverse effects of perioperative blood transfusion on outcome of patients undergoing ‘curative’resection for gastric cancer.