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ORANGE/BLACK DISCOLOURATION OF THE BOWEL (AT LAPAROTOMY) DUE TO CLOFAZIMINE
Author(s) -
Merrett M. N.,
King R. W. F.,
Farrell K. E.,
Zeimer H.,
Guli E.
Publication year - 1990
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1990.tb07446.x
Subject(s) - medicine , clofazimine , exacerbation , pyoderma gangrenosum , inflammatory bowel disease , surgery , laparotomy , orange (colour) , dermatology , disease , leprosy , horticulture , biology
Clofazimine, a commonly used anti‐lepromatous drug, is now being prescribed for the treatment of pyoderma gangrenosum, a complication of inflammatory bowel disease. This drug can cause an obstructive exacerbation of Crohn's disease. Surgeons should be aware of the orange/black discolouration of the bowel, which may mimic ischaemia macroscopically. A case, the first reported in Australia, is described and the literature discussed.