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AN IMMUNOHISTOLOGICAL EXAMINATION OF INFLAMMATORY CELL INFILTRATION IN PRIMARY TESTICULAR SEMINOMAS
Author(s) -
Strutton G. M.,
Gemmell E.,
Seymour G. J.,
Walsh M. D.,
Lavin M. F.,
Gardiner R. A.
Publication year - 1989
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1989.tb01491.x
Subject(s) - cytotoxic t cell , medicine , infiltration (hvac) , antigen , pathology , immunohistochemistry , population , immunology , biology , in vitro , biochemistry , physics , environmental health , thermodynamics
Inflammatory cell infiltration was characterized in five classical seminomatous testicular tumours using immunohistochemical techniques. These cells of immunological lineage were sited mostly around vessels. Lymphocytes were the most numerous, t cells outnumbering b cells in all sections studied. The helper/inducer subgroup predominated in the t cell family with suppressor cells more common than cytotoxic cells. Plasma cells constituted only a small percentage of this population as did natural killer cells. No langerhans cells were identified. Phagocytic macrophages were twice as common as antigen‐presenting macrophages yet t lymphocytes were 15 times more common than these antigen‐presenting macrophages.