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CONTROLLED CLINICAL TRIAL OF RANITIDINE IN BLEEDING PEPTIC ULCER
Author(s) -
Gray Bruce N.,
Zwart Jill De,
Andrewarthur Louise,
Crowley Simon,
Kamm Michael,
Watson Katrina
Publication year - 1986
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1986.tb02380.x
Subject(s) - medicine , ranitidine , duodenum , peptic ulcer , placebo , peptic , randomized controlled trial , stomach , population , gastroenterology , surgery , anesthesia , alternative medicine , environmental health , pathology
One hundred and two patients were entered into controlled, randomized clinical trial to assess the value of ranitidine versus placebo, given immediately after entry to hospital to modify the outcome of patients admitted to hospital with acute bleeding from peptic ulceration of the stomach or duodenum. The results indicated that ranitidine could not significantly modify the blood requirements, rebleeding rate or operation rate in this patient population during the initial hospital admission.