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EXPERIMENTAL SPLENOSIS: A COMPARATIVE STUDY IN RATS
Author(s) -
LAU JAMES T. K.,
ONG G. B.
Publication year - 1982
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1982.tb06104.x
Subject(s) - medicine , splenectomy , pouch , spleen , surgery , blood supply
The growth of the splenic remnant after partial splenectomy and autogenous splenic Implants was compared in immature rats. Implants placed in the subcutaneous pouch of the anterior abdominal wall and the retroperitoneal space had none or minimal regeneration. Splenules formed in the omental wrap were small, multiple and the combined weight was less than the original grafted tissue, and more ectopic splenules and intra‐abdominal adhesions were formed. Splenic remnants after three‐quarter splenectomy with an intact blood supply grew to 30–46% of the weight of the spleen of the control; and increased in size as the animal matured