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CYCLIC AMP AND GASTRIC ACID SECRETION IN THE DOG
Author(s) -
HALL JOHN C.,
JERUMS G.,
DOUGLAS M. C.
Publication year - 1982
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1982.tb05401.x
Subject(s) - pentagastrin , medicine , gastric acid , secretion , endocrinology
Canine gastric secretions were collected for acid and cyclic AMP assay at zero, 15, 30, 45 and 60 minutes during intravenous infusion of zero, 2.5 and 5.0 μg/kg/hr of pentagastrin. A resulting brisk acid response was not accompanied by an elevation of cyclic AMP content. It is thereby suggested that cyclic AMP may not be an obligatory intermediary for gastric acid secretion.