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LONG‐TERM HIGH‐DOSE MEBENDAZOLE FOR CYSTIC HYDATID DISEASE OF LIVER: FAILURE IN TWO CASES
Author(s) -
BRAITHWAITE PETER A.
Publication year - 1981
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1981.tb05897.x
Subject(s) - mebendazole , medicine , disease , echinococcosis , surgery , cystic echinococcosis , ecology , biology
Mebendazole was given as definitive therapy to four patients with cystic hydatid disease of the liver who were later explored surgically. Viable hydatid material was removed from two patients after continuous therapy with 40 mg/kg/day for eight and three months respectively. The hydatid material was necrotic in the of her two patients. This drug appeared to be ineffective as definitive treatment of two of these four patients with established hydatid disease of the liver.