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LIMB SALVAGE USING PREOPERATIVE INTRAARTERIAL ADRIAMYCIN AND RADIATION THERAPY FOR EXTREMITY SOFT TISSUE SARCOMAS
Author(s) -
MORTON DONALD L.,
EILBER FREDERICK R.,
WEISENBURGER THOMAS H.,
TOWNSEND COURTNEY M.,
MlRRA JOSEPH M.
Publication year - 1978
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1978.tb05806.x
Subject(s) - medicine , soft tissue , radiation therapy , surgery , radiology , adjuvant therapy , sarcoma , soft tissue sarcoma , chemotherapy , pathology
Surgical therapy has been the accepted method for management of most soft tissue sarcomas of the extremities, although it has been associated frequently with local treatment failure. Even when local control was achieved, over 50% of the patients with soft tissue sarcomas eventually developed and succumbed to distant metastases of their disease. Therefore, single modality therapy for soft tissue sarcomas by operation alone results in an unacceptably high incidence of treatment failure. Fortunately, new adjuvant treatment techniques have been developed that seem to have activity against these neoplasms. It is the purpose of this article to discuss our experience with a number of these techniques.