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HORMONE RECEPTORS AND BREAST CANCER
Author(s) -
KEIGHTLEY D.D.
Publication year - 1978
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1978.tb05227.x
Subject(s) - medicine , breast cancer , hormone , pregnancy , physiology , cancer , endogeny , reproduction , hormone receptor , gynecology , oncology , obstetrics , biology , ecology , genetics
The hormones of reproduction have been implicated in breast cancers of women. A short reproductive life, and a pregnancy prior to the age of 30 years, both reduce the risk of breast cancer (Doll, 1975). In addition, removal of endogenous sources of oestrogens, and administration of anti‐oestrogens, cause some breast cancers to regress (Stoll, 1969). Such observations have led to an investigation of the role of the hormones of reproduction, and of oestrogen in particular, in the maintenance of breast cancers.