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HEPATIC METASTASES FROM COLORECTAL CARCINOMA: AN ANALYSIS OF SURVIVAL RATES AND HISTOPATHOLOGY 1
Author(s) -
Morris M. J.,
Newland R. C.,
Pheils Murray T.,
Macpherson J. G.
Publication year - 1977
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1977.tb04304.x
Subject(s) - medicine , histopathology , colorectal cancer , oncology , gastroenterology , pathology , cancer
Out of 338 patients undergoing laparotomy and resection of a primary colorectal carcinoma, 49 (14.5%) were found to have liver metastases. The average age was 70 years. The median period of survival was 11.4 months. The histological grade of malignancy of the primary tumour did not appear to influence the survival rate. Compared with similar tumours in patients without hepatic metastases, the primary growth showed a significantly increased incidence of venous invasion, a higher grade of malignancy, and a more frequent origin from the right colon. When the local spread of the primary tumours was investigated it was found that one‐third of them had not progressed beyond Stage Dukes A or B.