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THE ROLE OF BRADYKININ IN ENDOTOXIC SHOCK OF INTESTINAL ORIGIN
Author(s) -
Fink R. L. W.,
Mashford M. L.,
Caridis D. T.
Publication year - 1977
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1977.tb03946.x
Subject(s) - medicine , bradykinin , endotoxic shock , shock (circulatory) , receptor
A relationship was looked for between blood levels of bradykinin and endotoxæmia produced by superior mesenteric artery occlusion in the rabbit. The levels of bradykinin were unrelated to and unaltered by the degree of endotoxæmia observed in the systemic and portal circulations. These findings suggest that bradykinin is not responsible for the release of endotoxin from the gut, or for the circulatory collapse which follows.